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N male rats.Parameter Duration of aggression/sec GROUP Control Leaded gasoline Unleaded gasoline Tooth chattering 0.9 ?0.23 4.7 ?1.1 a** 4.4 ?0.92 a* Threat posture 1.5 ?0.54 6 ?1.2 a* 6.2 ?1.31 a* Leaping and biting 1.9 ?0.72 5.5 ?1.45 5.9 ?1.50 Boxing position 1 ?0.42 2.2 ?0.63 2.2 ?0.Values are expressed as means ?SE a: significantly different from the control group. Asterisks indicate the leve
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Is the study of Gutteridge and Halliwell [44] showing that Na+, K+-ATPase reduces its activity up to 50 due to oxidative stress. The present findings show that the rats exhibited a decrease in the activity of AChE in the unleaded group in comparison with either the control or the leaded groups. In addition to its function in degrading acetylcholine and modulation of neural function; AChE as a str
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Ither the leaded or unleaded group as compared with the control. On the contrary, dopamine was elevated in the cerebellum of leaded exposed group above both the unleaded gasoline and control. The fluctuations in the levels of dopamine in different brain areas may be related to the effects MMT which is an organic manganese (Mn) compound added to unleaded gasoline and the mechanisms of Mn neurotoxic
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Sible to interpret these results in the light of the effects of gasoline constituents. Another study demonstrated that lead exposure enhances predatory aggression in the cat and provide experimental support for a causal relationship between lead exposure and aggressive behaviour in humans [56]. This was concomitant with deficiency in serotonin that plays an important role to counteract the aggress
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N.edu 1 Department of Pathology (Neuropathology), Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USAnoted that the striking increases in AD and PD mortality rates followed sharply increased consumption of processed foods, use of preservatives, and demand for nitrogen-containing fertilizers [4]. A common theme resonating from these unnecessary lifestyle trends is that we have inadver
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Is the study of Gutteridge and Halliwell [44] showing that Na+, K+-ATPase reduces its activity up to 50 due to oxidative stress. The present findings show that the rats exhibited a decrease in the activity of AChE in the unleaded group in comparison with either the control or the leaded groups. In addition to its function in degrading acetylcholine and modulation of neural function; AChE as a str
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Anied with a higher tendency towards aggressive behaviour as a consequence to gasoline inhalation.11. 12.13. 14.AbbreviationsNa+, K+-ATPase: total adenosine triphosphatase; SOD: superoxide dismutase; AChE: acetylcholinesterase; GSH: reduced glutathione; TBARS: lipid peroxidation; DA: dopamine; NE: norepinephrine; 5-HT: serotonin; CNS: central nervous system; ROS: reactive oxygen species; MMT: meth